We describe the hyperboloidal compactification for Teukolsky equations in Kerr spacetime. We include null infinity on the numerical grid by attaching a hyperboloidal layer to a compact domain surrounding the rotating black hole and the orbit of an inspiralling point particle. This technique allows us to study, for the first time, gravitational waveforms from large-and extreme-mass-ratio inspirals in Kerr spacetime extracted at null infinity. Tests and comparisons of our results with previous calculations establish the accuracy and efficiency of the hyperboloidal layer method.